This data supports the following publication: Rose, K.C., S.R. Greb, M. Diebel, and M.G. Turner. Annual precipitation as a regulator of spatial and temporal drivers of lake water clarity. Ecological Applications. The data uses satellite remotely sensed estimates of Secchi disk depth (Landsat imagery), landscape features, and lake characteristics to understand how and why lakes vary and respond to different drivers through time and space. The data were produced by the authors and their collaborators, as acknowledged in the manuscript. The Secchi disk depth data span the time period 1991-2012.